Mackenzie Graham is a Research Fellow in Neuroethics, at the Oxford Uehiro Centre for Practical Ethics, and the Wellcome Centre for Ethics and Humanities. Mackenzie received a PhD in Philosophy from The University of Western Ontario, in London Canada, and was previously a Post-Doctoral Associate at the Brain and Mind Institute at Western. His research interests are in moral philosophy and neuroethics, particularly in the challenges of evaluating the well-being of individuals who are behaviourally non-responsive as a result of severe brain injury. His project investigates how can we assess well-being in patients whose means of communication are severely limited or non-existent, what actions can and should we take to promote their well-being, and questions pertaining to their moral status.
He has also written about clinical equipoise, disclosure of research results in functional neuroimaging research, and accidental awareness during general anaesthesia.
Journal Articles:
Graham M, Owen AM, Weijer C, Naci L. 2017. Using neuroimaging to detect covert awareness in the severely brain-injured and patients who become accidentally aware under general anesthesia. Frontiers in Bioscience, In Press.
Graham M. 2017. ‘A fate worse than death? The well-being of patients diagnosed as vegetative with covert awareness.’ Ethical Theory and Moral Practice, 20(5): 1005-1020.
Graham M, Owen AM, Kaman C, Weijer C, Naci L. 2017. ‘Minimizing the harm of accidental awareness during general anesthesia: A novel perspective from patients misdiagnosed as being in a vegetative state.’ Anesthesia & Analgesia, DOI: 10.1213/ANE.0000000000002495 [Epub ahead of print]
Graham M, Naci L, Weijer C, Owen AM. 2017. ‘Covert narrative capacity: Mental life of patients thought to lack consciousness.’ Annals of Clinical and Translational Neurology, 4(1): 61-70.
Graham M, Weijer C, Cruse D, Fernandez-Espejo D, Gofton T, Gonzalez-Lara L, Naci L, Norton, L, Peterson A, Speechley KN, Young B, Owen AM. 2015. ‘An ethics of welfare for patients diagnosed as vegetative with covert awareness.’ American Journal of Bioethics- Neuroscience, 6(2): 31-41.
Graham M, Weijer C, Peterson A, Naci L, Cruse D, Fernandez-Espejo D, Gonzalez-Lara L, Owen AM. 2015. ‘Acknowledging awareness: Informing families of individual research results for patients in the vegetative state.’ Journal of Medical Ethics, 41(7): 534-538.
Weijer C, Peterson A, Webster F, Graham M, Cruse D, Fernandez-Espejo D, Gofton T, Gonzalez-Lara LE, Lazosky A, Naci L, Norton, L, Speechley K, Young B, Owen, AM. 2014. ‘Ethics of Neuroimaging after serious brain injury’. BMC Medical Ethics, 15(1): 41-54.
Peterson A, Naci, L, Weijer C, Cruse D, Fernandez-Espejo D, Graham M, Owen AM. 2013. ‘Assessing decision-making capacity in the behaviorally non-responsive patient with residual covert awareness.’ American Journal of Bioethics-Neuroscience, 4(4): 3-14.
Book Chapters:
Weijer C, Miller PB, Graham M. 2015. ‘The Duty of Care and Equipoise in Randomized Controlled Trials’. The Routledge Companion to Bioethics. Arras JD, E Fenton, R Kukla, (eds.) New York: Routledge.
